Fig. 2

Histopathological findings of the surgical specimens. a Widespread infarction (hematoxylin and eosin staining, ×2); b Tumor fibrin embolism in a pulmonary arteriole (hematoxylin and eosin staining, ×10); c Fibrocellular intimal proliferation (elastic van Gieson staining, ×10); d Tumor cells (at increased magnification, hematoxylin and eosin staining, ×60); and e Tumor cells demonstrating HER2 positivity (immunohistochemical staining, ×60)