Genotype | Tumor size (≤3 cm/4–5 cm/≥6 cm) | Depth of tumor invasion ((Tis + T1)/T2/T3/T4) | Regional lymph node metastasis (N0/N1/N2/N3) | Distant metastasis (M0/M1) | TNM classification ((0 + I)/II/III/IV) | |||||
---|---|---|---|---|---|---|---|---|---|---|
OR (95Â % CI) | P | OR (95Â % CI) | P | OR (95Â % CI) | P | OR (95Â % CI) | P | OR (95Â % CI) | P | |
rs13042395 | ||||||||||
 CC | 1.00 (Reference) |  | 1.00 (Reference) |  | 1.00 (Reference) |  | 1.00 (Reference) |  | 1.00 (Reference) |  |
 CT | 1.17 (0.73–1.86) | 0.53 | 0.90 (0.52–1.55) | 0.71 | 0.83 (0.52–1.33) | 0.45 | 0.83 (0.14–5.04) | 0.84 | 0.79 (0.41–1.26) | 0.33 |
 TT | 1.18 (0.67–2.06) | 0.57 | 0.82 (0.43–1.56) | 0.55 | 0.55 (0.31–0.98) | 0.04 | 0.59 (0.05–6.63) | 0.67 | 0.72 (0.49–1.27) | 0.25 |
 CT + TT | 1.17 (0.75–1.82) | 0.49 | 0.88 (0.52–1.46) | 0.61 | 0.73 (0.47–1.14) | 0.16 | 0.75 (0.14–4.17) | 0.74 | 0.76 (0.49–1.20) | 0.24 |
 CC + CT | 1.00 (Reference) |  | 1.00 (Reference) |  | 1.00 (Reference) |  | 1.00 (Reference) |  | 1.00 (Reference) |  |
 TT | 1.07 (0.67–1.70) | 0.79 | 0.88 (0.52–1.50) | 0.63 | 0.62 (0.38–1.01) | 0.06 | 0.66 (0.08–5.77) | 0.71 | 0.84 (0.52–1.34) | 0.46 |
rs3746803 | ||||||||||
 GG | 1.00 (Reference) |  | 1.00 (Reference) |  | 1.00 (Reference) |  | 1.00 (Reference) |  | 1.00 (Reference) |  |
 GA + AA | 1.1 (0.57–2.09) | 0.78 | 1.4 (0.65–3.00) | 0.39 | 1.06 (0.55–2.03) | 0.87 | 1.73 (0.20–15.02) | 0.62 | 1.3 (0.67–2.51) | 0.43 |