Single nucleotide polymorphism rs13042395 in the SLC52A3 gene as a biomarker for regional lymph node metastasis and relapse-free survival of esophageal squamous cell carcinoma patients

Table 2 Association between SNPs in SLC52A3 and ESCC risk in the Chinese population (N_ESCC = 479, N_control = 479)

Genotype	ESCC	Control	OR (95 % CI)	P
Genotype	N (%)	N (%)	OR (95 % CI)	P
rs13042395
CC	135 (28.18)	147 (30.69)	1.00 (reference)
CT	236 (49.27)	218 (45.51)	1.18 (0.88–1.59)	0.28
TT	108 (22.55)	114 (23.80)	1.03 (0.73–1.47)	0.86
CT + TT	344 (71.82)	332 (69.31)	1.14 (0.86–1.50)	0.36
CC + CT	371 (77.45)	365 (76.20)	1.00 (reference)
TT	108 (22.55)	114 (23.80)	0.93 (0.69–1.26)	0.65
rs3746803
GG	425 (88.73)	424 (88.52)	1.00 (reference)
GA	55 (11.48)	53 (11.06)	1.00 (0.67–1.49)	0.99
AA	1 (0.21)	2 (0.42)	0.50 (0.05–5.52)	0.57
GA + AA	54 (11.27)	55 (11.48)	0.98 (0.66–1.46)	0.92
GG + GA	478 (99.79)	477 (99.58)	1.00 (reference)
AA	1 (0.21)	2 (0.42)	0.50 (0.05–5.52)	0.57

All associations are significant at P < 0.05
SNP single nucleotide polymorphism, ESCC esophageal squamous cell carcinoma, OR odds ratio, 95 % CI 95 % confidence interval

ISSN: 1471-2407