The combined expression of Semaphorin4D and PlexinB1 predicts disease recurrence in colorectal cancer

BMC Cancer

Table 3 Correlations between clinicopathological findings and the combination of Sema4D and PlexinB1 expresion

Variables	Sema4D and PlexinB1 expression		p value
	Both positive	Others
	(n = 63)	(n = 163)
Age (years)
Mean ± SD	68.1 ± 10.2	66.0 ± 11.7	0.351
Gender
Male	35	89	0.897
Female	28	74	0.897
Stage
I	7	51	<0.001
II	11	46	<0.001
III	45	66
Histology
Well/mod	53	149	0.123
Other	10	14	0.123
Depth of tumor invasion
T1/T2	10	58	0.002
T3/T4	53	105	0.002
Lymph node metastasis
negative	18	96	<0.001
positive	45	67	<0.001
Lymphatic invasion
Negative	9	69	<0.001
Positive	54	94	<0.001
Venus invasion
Negative	41	146	<0.001
Positive	22	17	<0.001

Sema4D semaphorin 4D. Other poorly-differnetiated, mucinous-type, small-cell, signet-cell

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