Fig. 2

Coverage and intensity of HAS1 and HAS2 immunostainings in melanoma cells of superficial melanoma (pT1), deep melanoma (pT4) and lymph node metastasis (pN1-). Coverage and intensity of HAS1 immunostainings were successfully recorded from 112 samples. Coverage and intensity of HAS2 immunostainings were recorded from 110 samples. Statistically significant differences between the stages are indicated with brackets (Mann–Whitney U test). * p-value < 0.05, ** p-value <0.01, *** p-value <0.001