Characteristic | Univariate | Adjusted | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | Advanced 95% CI | p | OR | Metastatic 95% CI | p | OR | Advanced 95% CI | p | OR | Metastatic 95% CI | p | |
Age | ||||||||||||
<40 | 1.70 | 1.43–2.02 | 1.63 | 1.15–2.31 | 1.10 | 0.92–1.32 | 1.03 | 0.70–1.50 | ||||
40–49 | Ref | 0.000 | Ref | 0.000 | Ref | 0.000 | Ref | 0.021 | ||||
50–59 | 0.76 | 0.67–0.86 | 0.81 | 0.62–1.05 | 1.10 | 0.96–1.26 | 1.24 | 0.93–1.65 | ||||
60–69 | 0.59 | 0.51–0.67 | 0.78 | 0.60–1.03 | 0.90 | 0.78–1.05 | 1.19 | 0.88–1.61 | ||||
70–79 | 0.84 | 0.72–0.98 | 1.51 | 1.15–1.99 | 0.85 | 0.72–1.00 | 1.50 | 1.10–2.04 | ||||
80+ | 0.98 | 0.83–1.16 | 1.72 | 1.29–2.32 | 0.76 | 0.63–0.91 | 0.84 | 0.59–1.21 | ||||
Year of diagnosis | ||||||||||||
2000–2003 | Ref | 0.068 | Ref | 0.079 | Ref | 0.311 | Ref | 0.042 | ||||
2004–2006 | 1.09 | 0.96–1.24 | 1.22 | 0.94–1.59 | 0.93 | 0.80–1.08 | 1.19 | 0.87–1.64 | ||||
2007–2009 | 1.07 | 0.94–1.21 | 1.37 | 1.07–1.76 | 0.95 | 0.81–1.12 | 1.51 | 1.10–2.07 | ||||
2010–2013 | 0.94 | 0.83–1.06 | 1.29 | 1.01–1.65 | 0.87 | 0.75–1.02 | 1.44 | 1.06–1.96 | ||||
Region | ||||||||||||
Auckland | Ref | 0.004 | Ref | 0.000 | Ref | 0.741 | Ref | 0.903 | ||||
Waikato | 1.16 | 1.05–1.29 | 1.43 | 1.18–1.72 | 1.03 | 0.85–1.24 | 0.98 | 0.68–1.42 | ||||
Ethnicity | ||||||||||||
NZ European | Ref | Ref | Ref | Ref | ||||||||
Maori | 1.58 | 1.37–1.82 | 0.000 | 2.14 | 1.68–2.73 | 0.000 | 1.27 | 1.08–1.49 | 0.004 | 1.86 | 1.39–2.49 | 0.000 |
Pacific | 2.27 | 1.95–2.65 | 0.000 | 3.38 | 2.64–4.35 | 0.000 | 1.72 | 1.43–2.06 | 0.000 | 2.81 | 2.03–3.87 | 0.000 |
Asian | 0.96 | 0.81–1.14 | 0.639 | 0.88 | 0.61–1.26 | 0.475 | 0.81 | 0.67–0.98 | 0.026 | 0.90 | 0.61–1.33 | 0.609 |
Other | 0.76 | 0.55–1.04 | 0.755 | 1.10 | 0.64–1.90 | 0.737 | 0.87 | 0.62–1.23 | 0.426 | 1.56 | 0.86–2.83 | 0.146 |
Unknown | 0.31 | 0.17–0.60 | 0.000 | 0.15 | 0.02–1.05 | 0.056 | 0.37 | 0.19–0.72 | 0.003 | 0.22 | 0.03–1.63 | 0.139 |
Deprivation | ||||||||||||
1–2 | Ref | 0.000 | Ref | 0.000 | Ref | 0.000 | Ref | 0.017 | ||||
3–4 | 0.99 | 0.85–1.16 | 1.08 | 0.78–1.48 | 0.96 | 0.81–1.14 | 0.84 | 0.59–1.19 | ||||
5–6 | 1.09 | 0.95–1.26 | 1.21 | 0.91–1.63 | 1.05 | 0.90–1.23 | 0.99 | 0.71–1.36 | ||||
7–8 | 1.45 | 1.26–1.66 | 1.79 | 1.36–2.36 | 1.31 | 1.12–1.53 | 1.40 | 1.02–1.92 | ||||
9–10 | 1.57 | 1.37–1.80 | 2.18 | 1.67–2.84 | 1.28 | 1.09–1.51 | 1.40 | 1.01–1.92 | ||||
Unknown | 0.80 | 0.46–1.36 | 1.26 | 0.50–3.18 | 0.79 | 0.14–4.47 | 0.94 | 0.01–109 | ||||
Urban rural | ||||||||||||
Main urban | Ref | 0.009 | Ref | 0.001 | Ref | 0.981 | Ref | 0.004 | ||||
Other urban | 0.91 | 0.74–1.10 | 1.40 | 1.01–1.93 | 1.03 | 0.83–1.29 | 2.00 | 1.37–2.92 | ||||
Rural | 1.16 | 1.04–1.30 | 1.48 | 1.21–1.81 | 1.01 | 0.82–1.25 | 1.22 | 0.83–1.82 | ||||
Unknown | 0.66 | 0.40–1.11 | 0.90 | 0.37–2.28 | 0.78 | 0.15–4.18 | 0.40 | 0.01–46.1 | ||||
Mode of detection | ||||||||||||
Screen | Ref | 0.000 | Ref | 0.000 | Ref | 0.000 | Ref | 0.000 | ||||
Non−screen | 4.83 | 4.28–5.44 | 8.18 | 6.13–10.9 | 3.79 | 3.33–4.34 | 6.03 | 4.41–8.24 | ||||
ER/PR status | ||||||||||||
ER/PR Positive | Ref | 0.000 | Ref | 0.000 | Ref | 0.070 | Ref | 0.620 | ||||
ER & PR Negative | 1.73 | 1.55–1.92 | 1.92 | 1.58–2.34 | 1.13 | 0.99–1.28 | 1.06 | 0.83–1.36 | ||||
Unknown | 1.60 | 1.23–2.08 | 5.45 | 4.00–7.45 | 1.50 | 1.06–2.14 | 1.12 | 0.71–1.79 | ||||
Grade | ||||||||||||
Grade I | Ref | 0.000 | Ref | 0.000 | Ref | 0.000 | Ref | 0.000 | ||||
Grade II | 3.73 | 3.13–4.44 | 3.88 | 2.56–5.88 | 2.85 | 2.38–3.40 | 2.72 | 1.78–4.14 | ||||
Grade III | 7.00 | 5.88–8.35 | 7.76 | 5.12–11.7 | 4.13 | 3.30–5.00 | 3.85 | 2.47–5.99 | ||||
Unknown | 13.6 | 10.8–16.9 | 56.2 | 36.8–85.7 | 12.7 | 9.82–16.4 | 49.6 | 31.2–79.1 | ||||
HER-2 status | ||||||||||||
Negative | Ref | 0.000 | Ref | 0.000 | Ref | 0.000 | Ref | 0.000 | ||||
Equivocal | 0.83 | 0.57–1.22 | 0.61 | 0.25–1.49 | 0.73 | 0.48–1.10 | 0.46 | 0.18–1.19 | ||||
Positive | 2.36 | 2.10–2.66 | 2.65 | 2.13–3.28 | 1.57 | 1.38–1.79 | 1.80 | 1.41–2.31 | ||||
Unknown | 0.84 | 0.75–0.94 | 1.18 | 0.96–1.45 | 0.63 | 0.54–0.74 | 0.63 | 0.45–0.87 |