Table 6 BCNU-related side effects - Comparison of own results to the literature
Reference | Cytotoxic agent | Hematotoxicity | Pulmonary SE | CTH-related deaths (%) |
|---|---|---|---|---|
CTCAE III/IV (%) | CTCAE I - IV (%) | |||
Stupp (2005) [1] | TMZ (+RT) | 16 | - | - |
Buckner (2006) [27] | BCNU (+ RT) | L 28 | 10 | - |
T 44 | ||||
Weller (2003) [45] | BCNU (+WBRT) | - | 12 | 4 |
Weller (2003) [45] | ACNU/VM26 (+RT) | 36,5 | 0,7 | 2,6 |
Brandes (2004) [23] | BCNU | L 8 | ND | |
T 10 | 5 | |||
(WHO 3/4) | (WHO 4) | |||
own results | BCNU | L 1,8 | 0,6 | 0 |
T 3,6 |