Fig. 1
MR images of a patient receiving concurrent chemo-radiotherapy (CCRT) for advanced cervical cancer (FIGO stage IIIA). a Axial T2-weighted image before CCRT shows a hyperintense mass lesion (arrows) at the cervix, with a maximal diameter of 6.0 cm. b ADC map corresponding to (a) shows a low ADC value (0.933 × 10−3 mm2/s) of the lesion compared with the adjacent normal cervical tissues (1.54 × 10−3 mm2/s). c The f map corresponding to (a) shows a low f value (0.097) of the lesion compared with the adjacent normal cervical tissues (0.198); d Two weeks after initiation of CCRT, the diameter of cervical cancer decreased to 4.2 cm. e The ADC value of the lesion corresponding to (d) increased to 1.038 × 10−3 mm2/s compared with (b). f The f value of the lesion corresponding to (d) increased to 0.116 compared with (c). g One month after initiation of CCRT, the lesion continues to decrease with a diameter of 1.7 cm. h The ADC value of the lesion corresponding to (g) continues to increase to 1.563 × 10−3 mm2/s compared to (e). i The f value of cervical cancer corresponding to (g) continues to increase to 0.239 compared to (f). j Post CCRT, no residual lesion is observed in the axial T2-weighted image. k The ADC value of the lesion corresponding to (j) continues to increase to 1.737 × 10−3 mm2/s compared to (h). l The f value of cervical cancer corresponding to (g) continues to increase to 0.165 compared to (i)