From: HOX transcription factors are potential targets and markers in malignant mesothelioma
Cell line | Source | IC50 HXR9 (μM) | Ref |
---|---|---|---|
Met-5a | Normal mesothelium cells from pleural fluid | 98 | [34] |
NCI-H28 | Pleural effusion | 18 | ATCC |
MSTO-211H | Biphasic mesothelioma (fibroblast morphology) | 28 | [35] |
NCI-H2052 | Pleural effusion (epithelial morphology) | 45 | ATCC |
NCI-H226 | Squamous carcinoma; mesothelioma (epithelial morphology). This cell line was derived from non-small cell lung cancer, although it was subsequently found to have a number of mesothelioma-related properties, including the expression of mesothelin. | 107 | ATCC, [36] |