Fig. 4
From: HOX transcription factors are potential targets and markers in malignant mesothelioma
Mechanisms of cell death. a Induction of cFos in mesothelioma-derived cell lines. The amount of cFos RNA was determined by QPCR in cells either untreated or treated with HXR9 or CXR9 for 2 h at the IC50 for each. Expression is shown relative to Beta-actin (×10000). The values are the means of three experiments, error bars show the SEM. *** indicates a p < 0.001 compared to cFos expression in untreated cells. b Caspase 3 activation in NCI-H28 cells and Met-5A cells (c). The values are the means of three experiments, error bars show the SEM. * indicates a p < 0.05 compared to caspase 3 activity in untreated cells