Table 2 Toxicity possibly, probably, or definitely attributable to chemotherapy (n = 51)
Adverse events | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Total | |||||
|---|---|---|---|---|---|---|---|---|---|---|
No. of patients | (%) | No. of patients | (%) | No. of patients | (%) | No. of patients | (%) | No. of patients | (%) | |
Hematological | ||||||||||
Leucopenia | 15 | 29.4 | 17 | 33.3 | 1 | 1.96 | 1 | 1.96 | 34 | 66.7 |
Neutropenia | 13 | 25.5 | 13 | 25.5 | 5 | 9.8 | 2 | 3.9 | 33 | 64.7 |
Anemia | 12 | 23.5 | 10 | 19.6 | 3 | 5.9 | 0 | 0 | 25 | 49.0 |
Thrombocytopenia | 7 | 13.7 | 11 | 21.6 | 7 | 13.7 | 4 | 7.8 | 29 | 56.9 |
Non-hematological | ||||||||||
Hepatic dysfunction | 19 | 37.3 | 3 | 5.9 | 1 | 1.9 | 0 | 0 | 23 | 45.1 |
Nausea/vomiting | 15 | 29.3 | 11 | 21.6 | 2 | 3.9 | 0 | 0 | 28 | 54.9 |
Neurotoxicity | 12 | 23.5 | 3 | 5.9 | 2 | 3.9 | 0 | 0 | 17 | 13.7 |
Hand-food syndrome | 12 | 23.5 | 5 | 9.8 | 2 | 3.9 | 0 | 0 | 19 | 37.3 |
Anorexia | 8 | 15.7 | 0 | 0 | 1 | 1.9 | 0 | 0 | 9 | 17.6 |
Diarrhea | 5 | 9.8 | 4 | 7.8 | 2 | 3.9 | 0 | 0 | 11 | 21.6 |
Infusion reaction | 3 | 5.9 | 2 | 3.9 | 0 | 0 | 0 | 0 | 5 | 9.8 |
Fatigue | 1 | 1.9 | 3 | 5.9 | 1 | 1.9 | 0 | 0 | 5 | 9.8 |
Arrhythmia | 2 | 3.9 | 3 | 5.9 | 0 | 0 | 0 | 0 | 5 | 9.8 |