Table 2 Patients characteristics

Sex, n (%)

   Female

110 (27.0)

   Male

297 (73.0)

Mean age (SD), years

61.9 (12.0)

ECOG PS, n (%)

370

   0

110 (29.7)

   1

206 (55.7)

   2

44 (11.9)

   3

10 (2.7)

Histology, n (%)

399

   Clear cell

357 (89.5)

   Papillary

21 (5.3)

   Cromophobe

9 (2.3)

   Sarcomatoid

4 (1.0)

   Mixed

3 (0.8)

   Collecting Duct

1 (0.3)

   Others

4 (1.0)

*Targeted treatment, n (%)

   Sunitinib

251 (61.7)

   Sorafenib

62 (15.2)

   Pazopanib

56 (13.8)

   Everolimus

70 (17.2)

   Temsirolimus

37 (9.1)

   Bevacizumab

5 (1.2)