Table 2 Pharmacokinetic parameters according to metabolizer phenotype

41.44 ± 23.35

75.39 ± 15.74*

40.48 ± 6.37*

22.11 ± 8.15*

141.88 ± 86.78

218.14 ± 101.90*

152.69 ± 48.83*

80.78 ± 27.24*

157.12 ± 87.24

231.55 ± 100.02*

166.35 ± 55.59*

95.81 ± 28.38*

509.20 ± 265.57

345.49 ± 119.94*

480.93 ± 152.07*

834.97 ± 249.52*

9.81 ± 6.58

9.64 ± 6.18

10.76 ± 7.54

8.71 ± 5.43

0.071 ± 0.035

0.072 ± 0.041*

0.064 ± 0.030*

*0.080 ± 0.035