COBAS | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
All ages | Age <30 year | Age ≥30 year | ||||||||
Positive | Negative | Total | Positive | Negative | Total | Positive | Negative | Total | ||
HC2 | Positive | 410 | 106 | 516 | 108 | 14 | 122 | 302 | 92 | 394 |
Negative | 132 | 5,524 | 5,656 | 20 | 316 | 336 | 112 | 5,208 | 5,320 | |
Total | 542 | 5,630 | 6,172 | 128 | 330 | 458 | 414 | 5,300 | 5,714 | |
Overall agreement (95 % CI) | 96.1 % (95.6, 96.6) | 92.6 % (89.7, 94.7) | 96.4 % (95.9, 96.9) | |||||||
Kappa (95 % CI) | 0.75 (0.72, 0.79) | 0.81 (0.75, 0.87) | 0.73 (0.69, 0.76) | |||||||
Positive agreement (95 % CI) | 77.5 % (74.7, 80.3) | 86.4 % (81.9, 90.9) | 74.8 % (71.4, 78.1) | |||||||
Negative agreement (95 % CI) | 97.9 % (97.6, 98.2) | 94.9 % (93.2, 96.6) | 98.1 % (97.8, 98.3) |