Table 2 Cox uni- and multivariate analyses of associations between SUSD4 expression and known predictive markers for survival.

Survival tumor cells

Variable

N

HR

95 % CI

P

N

HR

95 % CI

P

 SUSD4 (no vs. yes)

122

0.41

0.2-0.9

0.042

107

0.34

0.1-0.9

0.040

 Age at diagnosis

144

1.05

1.0-1.1

0.003

107

1.05

1.0-1.1

0.008

 ER (neg vs. pos)

144

0.23

0.1-0.5

0.001

107

0.40

0.1-1.1

0.090

 NHG

144

5.14

2.0-13.0

0.001

107

1.60

0.4-5.8

0.478

 Size (<20 vs. >20 mm)

144

3.04

1.2-7.8

0.020

107

2.37

0.6-9.1

0.209

 Ki67 (weak vs. strong)

124

4.26

1.4-12.8

0.010

107

1.65

0.4-6.6

0.483

Survival infil. cells

Variable

N

HR

95 % CI

P

N

HR

95 % CI

P

 SUSD4 (low vs. high)

122

0.12

0.02-0.9

0.039

108

0.25

0.03-2.0

0.192

 Age at diagnosis

144

1.05

1.0-1.1

0.003

108

1.03

1.0-1.06

0.125

 ER (neg vs. pos)

144

0.23

0.1-0.5

0.001

108

0.56

0.2-1.7

0.318

 NHG

144

5.14

2.0-13.0

0.001

108

2.14

0.6-7.8

0.250

 Size (<20 vs. >20 mm)

144

3.04

1.2-7.8

0.020

108

2.18

0.6-8.6

0.265

 Ki67 (weak vs. strong)

124

4.26

1.4-12.8

0.010

108

1.20

0.3-5.6

0.815