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Table 2 Patient and tumour characteristics of 309 cases of early breast cancer

From: Digital imaging in the immunohistochemical evaluation of the proliferation markers Ki67, MCM2 and Geminin, in early breast cancer, and their putative prognostic value

Clinico-pathological feature

Distribution (percentage of cases with data)

Age, years

 

 Median

58

 Range

28−85

 <50

92 (29.9 %)

 >50

216 (70.1 %)

Tumour size

 

 <2 cm

114 (41.3 %)

 2−5 cm

153 (55.4 %)

 >5 cm

9 (3.3 %)

 Not known

33

LN status

 Positive

132 (46.2 %)

 Negative

154 (53.8 %)

 Not known

23

Histological Grade

 

 1

56 (20.1 %)

 2

121 (43.4 %)

 3

102 (36.6 %)

 Not known

30

ER (Estrogen Receptor) status

 

 Positive

226 (75.6 %)

 Negative

73 (24.4 %)

 Not known

10

HER2 status (IHC 3+ or FISH + ve)

 

 Positive

26 (16.8 %)

 Negative

129 (83.2 %)

 Not known

154

Recurrence (Local, regional, distant or death when death was known to be caused by breast cancer)

 

 Total

111/309 (35.9 %)

 Median time to recurrence (years)

3.14

 Range (years)

0.05−19.05

Mortality

 

 Total deaths with known cause

148

 Deaths due to breast cancer

83 (56 %)

 Deaths with breast cancer present at death

57 (38.5 %)

 Deaths due to causes other than breast cancer

8 (5.4 %)

 Not known

12

Overall survival (years)

 

 Median

13.48

 Range

0.33−18.11

Follow-up (years)

 

 Median

13

 Range

1−17.2