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Fig. 1 | BMC Cancer

Fig. 1

From: Digital imaging in the immunohistochemical evaluation of the proliferation markers Ki67, MCM2 and Geminin, in early breast cancer, and their putative prognostic value

Fig. 1

Expression of proliferation markers in invasive breast cancers. Representative breast cancer cores from a consecutive TMAs showing low and high immunohistochemical staining for 3 proliferation markers Ki67 (a,b), MCM2 (e,f) and Geminin (i,j) (150X magnification). Distribution of IHC determined expression of Ki67 (c), MCM2 (g) and Geminin (k) across 309 primary breast carcinomas. The number of cases is indicated on the x-axis, while the percentage scoring for the respective marker is depicted in the y-axis. Correlation between light microscopic and digital image guided scores for Ki67 (d), MCM2 (h) and Geminin (l). The Spearman’s rank correlation coefficient and p-values are shown

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BMC Cancer

ISSN: 1471-2407

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