Table 3 Multivariate logistic regression model for pathological complete response

CHEK2 H371Y

(MT v WT)

3.01 (1.34-6.78)

0.008

Age

(≤50 v >50 years)

1.26 (0.99-1.61)

0.06

Tumor grade

(III v I + II)

2.28 (1.71-3.03)

<0.001

Tumor size

(<2 v ≥2 cm)

1.76 (1.38-2.24)

<0.001

Lymph nodes

(Negative v Positive)

2.10 (1.63-2.71)

<0.001

ER

(Negative v Positive)

1.99 (1.48-2.67)

<0.001

PgR

(Negative v Positive)

1.65 (1.21-2.26)

0.002

HER2

(Positive v Negative)

1.36 (1.05-1.75)

0.021

Trastuzumab use

(Yes v No)

2.42 (1.47-3.99)

0.001