Figure 5

Comparison of the frequency of mutations within hotspots identified in the study cohort using panel sequencing, compared to mutations identified using whole exome sequencing in the TCGA data. A) Mutations across mutational hotspots in the 46 genes in the panel, B) mutations in TP53, C) mutations in KRAS, and D) mutations in the Wnt signaling components APC and CTNNB1.