Table 1 Functional grouping of genes modulated at least 2 fold in E-cadherin or P-cadherin-expressing cells with respect to control cells.
From: Functional characterization of E- and P-cadherin in invasive breast cancer cells
231-E-cadherin | 231-P-cadherin | |||||
|---|---|---|---|---|---|---|
Gene function | Up | Down | All | Up | Down | All |
Basic cellular functions | 15 | 8 | 23 | 13 | 8 | 21 |
Cell cycle and Apoptosis | 3 | 14 | 17 | 2 | 4 | 6 |
Signal Transduction | 6 | 14 | 20 | 9 | 6 | 15 |
Adhesion & ECM | 1 | 8 | 9 | 2 | 3 | 5 |
Cytokines & Immune | 1 | 7 | 8 | 2 | 1 | 3 |
Metabolism | 7 | 2 | 9 | 4 | 2 | 6 |
Transcription related | 0 | 6 | 6 | 4 | 4 | 8 |
Motility & Cytoskeleton | 4 | 3 | 7 | 4 | 1 | 5 |
Unknown function | 3 | 5 | 8 | 2 | 8 | 10 |
TOTAL | 40 | 67 | 107 | 42 | 37 | 79 |