Figure 2

Expression of lymphocyte specific genes. A) Relative mRNA expression of four lymphocyte specific genes together with PDGFC expression as assessed by qRT-PCR. PDGFC (yellow circle), IL2RG (blue square), LTB (red square), FYB (green square) and IL32 (gray square) in all biopsies investigated. Serial number of biopsies is given below, non-neoplastic thyroid tissue (green), classical PTC (blue) and clinically aggressive PTC (red). B) Correlation between the semiquantitative histophatological examination and qRT-PCR of lymphocyte specific mRNA transcripts is illustrated. Categories is L0 = practically no lymphocytes, L1 = less than 10% of total number of cells, L2 = between 10-50% of total number of cells. IL2RG (blue square), LTB (red square), FYB (green square) and IL32 (gray square). Serial number of biopsies is given below, and the biosies are arranged according to the results from the histopatological assessment (L0, L1-L2), as illustrated.