Association between an 8q24 locus and the risk of colorectal cancer in Japanese

BMC Cancer

Table 1 Characteristics of cases and controls

Variables	Cases		Controls		p-values
Total	481		962
Sex					1.00
Male	300	62.4%	600	62.4%
Female	181	37.6%	362	37.6%
Age (years)					0.803
< 40	20	4.2%	39	4.1%
40-49	50	10.4%	105	10.9%
50-59	169	35.1%	328	34.1%
60-69	164	34.1%	353	36.7%
70-	78	16.2%	137	14.2%
Mean age (SD)	60 (10.2)		60 (9.86)
Site of Cancer
Colon	245	50.9%
Rectum	236	49.1%
Smoking					0.102
None	215	44.7%	493	51.3%
Low-moderate (< 20 pack-years)	59	12.3%	116	12.1%
Heavy (≥ 20 pack-years)	203	42.2%	345	35.9%
Unknown	4	0.8%	8	0.8%
Drinking					0.695
None	190	39.5%	383	39.8%
Low (< 5 g ethanl/day)	64	13.3%	125	13.0%
Moderate (5≤ and < 23 g ethanol/day)	85	17.7%	196	20.4%
High (≥ 23 g ethanol/day)	135	28.1%	243	25.3%
Unknown	7	1.5%	15	1.6%
Daily folate consumption					0.857
T1 (≤ 262.0 μg/day)	153	31.8%	286	29.7%
T2 (≤ 346.6 μg/day)	158	32.9%	318	33.1%
T3 (> 346.6 μg/day)	162	33.7%	341	35.5%
Unknown	8	1.7%	17	1.8%
Body-Mass Index (BMI) kg/m²					0.923
< 22.5	206	42.8%	397	41.3%
22.5 ≤ and < 25	157	32.6%	314	32.6%
25 ≤ and < 27.5	73	15.2%	162	16.8%
≥ 27.5	41	8.5%	79	8.2%
Unknown	4	0.8%	10	1.0%
Family history of colorectal cancer in the first degree relatives					0.014
No	453	94.2%	932	96.9%
Yes	28	5.8%	30	3.1%
Average recreational exercise					0.329
None	192	39.9%	349	36.3%
< 0.5 hour/day	194	40.3%	398	41.4%
0.5 ≤ hour/day	95	19.8%	215	22.4%

ISSN: 1471-2407