Table 4 Spearman correlations between 7 apoptosis biomarkers and 5 risk factors and 4 clinico-pathologic features1
From: Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma
FasL | Fas | FADD | pFADD | Caspase8 | Caspase10 | Bcl2 | |
|---|---|---|---|---|---|---|---|
Risk factors | |||||||
Male (yes) | 0.17** | 0.01 | 0.05 | 0.02 | -0.02 | 0.03 | 0.00 |
Age (yrs) | -0.01 | 0.02 | -0.06 | -0.05 | 0.10 | 0.00 | 0.00 |
Tobacco use (yes) | 0.17** | 0.05 | 0.08 | -0.07 | 0.00 | 0.10 | 0.02 |
Alcohol use (daily or weekly) | 0.00 | -0.02 | 0.20** | -0.09 | 0.13* | 0.09 | 0.02 |
Family history UGI cancer (yes) | -0.18** | -0.15* | 0.00 | 0.04 | -0.05 | 0.02 | -0.01 |
Clinico-pathologic features | |||||||
Tumor grade (I -- IV) | -0.10 | -0.20** | -0.18** | 0.08 | -0.07 | -0.19** | 0.02 |
Tumor stage (1 -- 4) | 0.00 | -0.14* | -0.05 | 0.10 | 0.01 | 0.03 | 0.03 |
Lymph node metastasis (yes) | 0.02 | 0.01 | -0.04 | 0.06 | 0.00 | 0.01 | 0.02 |
Degree differentiation (poor) | -0.15* | -0.26*** | -0.21** | 0.03 | -0.17** | -0.36*** | -0.30*** |