A role of BRCA1 and BRCA2germline mutations in breast cancer susceptibility within Sardinian population

BMC Cancer

Table 1 BRCA1 and BRCA2 mutational analysis

High risk: presence of a breast cancer patient diagnosed before age 50 years and having at least one first- or second-degree relative who is diagnosed with breast cancer before 50 years of age or ovarian cancer at any age). No high risk: presence of a breast cancer patient having at least one first- or second-degree relative who is diagnosed with breast cancer or ovarian cancer at any age. BC, breast cancer; OC, ovarian cancer; MBC, male breast cancer.
* including 112 families already reported in our previous studies

ISSN: 1471-2407