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Table 4 Effect of serum starvation of P20C and P20E cells on the expression of selected marker mRNAs.

From: Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR)

 

Fresh serum

Serum starvation

mRNA

P20C

P20E

P20C

P20E

 

C

MNF

C

MNF

C

MNF

C

MNF

CYP1A1

1.00

1.25

1.21

1.03

28.38**bb

10.18**abb

41.16**bb

25.36**abb

AhR

1.00

1.03

2.11*

1.74*

2.02**bb

1.46**bb

1.43**

1.67*

ErbB2

1.00

1.68*a

4.24**

2.07*a

4.24**bb

5.81**bb

5.41***bb

3.21*ab

HRG

1.00

1.84*a

11.82**

3.47*a

0.82

0.93b

0.51**bb

0.24**ab

PI3K

1.00

1.00

2.67*

2.64**

1.51**bb

1.90*b

3.72**bb

4.27***bb

TGF-α

1.00

1.10

1.49

1.18

0.98

0.80bb

0.23**bb

0.28**bb

TGF-β3

1.00

2.04**a

4.96***

2.87*a

7.03*b

7.65**bb

12.61**bb

8.41**ab

  1. Statistical symbols are: * different from control (C = 1.00) fresh serum P20C, a significant effect of MNF from the matched control, b significant effect of serum starvation. One symbol indicates P ≤ 0.05; two P ≤ 0.01; three P ≤ 0.001.
  2. Serum/medium was given 3 hrs prior to the test designated as "fresh medium." For "serum starvation" tests, the same batch of cells treated with fresh serum/medium were given serum-free medium after 48 hrs and the samples were harvested 24 hrs thereafter.
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BMC Cancer

ISSN: 1471-2407

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