Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma

BMC Cancer

Table 2 Molecular alterations of EGFR, PDGFRA and VEGFR2 in ASC patients.

Case	EGFR		PDGFRA		VEGFR2
	Mutations	IHC*	Mutations	IHC	IHC
1	Q787Q	-	P567P; V824V; IVS18-50insA	+++	++
2	Normal	+++	Normal	+++	-
3	Q787Q	+++	V824V; IVS18-50insA	+++	+++
4	Q787Q	+++	V824V; IVS18-50insA	+++	+++
5	Q787Q	+++	V824V; IVS18-50insA	+++	+++
6	Normal	+	Normal	+++	+++
7	Q787Q	+++	P567P; IVS14+3G>A	+++	++
8	Q787Q	-	Normal	+++	+++
9	Normal	-	Normal	+++	+++
10	Normal	+++	P567P	+++	+++
11	Normal	-	P567P	np	+++
12	Q787Q	-	Normal	+++	+++
13	Q787Q	-	Normal	++	+++
14	Normal	++	Normal	+++	++
15	Q787Q	+	Normal	+++	+++
16	Normal	+++	P567P	+++	+
17	Q787Q	-	P567P	++	+++
18	Normal	-	Normal	+++	+
19	Q787Q	+++	Normal	+++	++
20	Q787Q	-	Normal	+++	+++
21	Normal	+	P567P	np	+++
22	Normal	++	P567P	+++	+
23	Normal	+++	Normal	++	++
24	Q787Q	-	Normal	++	+
25	Q787Q	+	IVS14+49G>A	+++	+
26	Q787Q	-	P567P	+++	+++
27	Normal	-	Normal	np	++
28	Q787Q	++	Normal	++	+
29	Q787Q	-	Normal	+++	+
30	Normal	+++	Normal	++	+++

IHC: Immunohistochemistry; *: previously reported in [20]; np: not possible due to tissue limitation.

ISSN: 1471-2407