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Figure 5 | BMC Cancer

Figure 5

From: P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients

Figure 5

Apoptosis induced by DM4 in the presence or absence of BCRP inhibitor FTC in K562 and K562/BCRP cells. K562 (grey) and K562/BCRP (black) cells were treated with DM4 at 40 nM in the presence or absence of FTC (1 μM) for 48 h, and then stained with Annexin V/propidium iodide for flow cytometry. All experiments were done in triplicate.

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BMC Cancer

ISSN: 1471-2407

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