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Figure 2 | BMC Cancer

Figure 2

From: P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients

Figure 2

The sensitivity of HL60 and HL60/ADR cells to DM4 and AVE9633 with or without MRP inhibitor. HL60 and HL60/ADR cells were treated with AVE9633 (A) or DM4 (B) at different concentrations (3.125, 6.25, 12.5, 25, 50, 100 and 200 nM) in the presence or absence of MK571 (5 μM) for 72 h, then their viability was measured by an MTT assay. All experiments were done in triplicate.

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BMC Cancer

ISSN: 1471-2407

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