Table 1 Summary of the most frequent copy number gains and losses. Table listing the most frequent copy number gains and losses, sorted in decreasing order, in relation to tumor stage. Columns give the cytoband, start reporter, end reporter, size (Mbp), and candidate genes in the region.
From: Prognostic Impact of Array-based Genomic Profiles in Esophageal Squamous Cell Cancer
Cytoband | Start reporter | End reporter | Size (Mbp) | Candidate genes |
|---|---|---|---|---|
Gains (≥ 60%) | ||||
5p15.33 | RP11-811I15 | CTD-2296H22 | 1.8 | TERT |
7p22.3 | CTD-2245C5 | RP11-745M18 | 2.3 | MAD1L1, NUDT1 |
7p11.2 | RP11-449G3 | RP11-535N12 | 1.1 | |
8q24.13-q24.23 | RP11-150N13 | RP11-141J23 | 10.5 | MYC, WISP1 |
8q24.3 | CTD-2330C15 | CTD-2300I18 | 1.5 | FOXH1 |
10q26.3 | RP13-137A17 | RP11-1065F16 | 0.8 | |
11q13.3-11q13.4 | RP11-433A18 | RP11-574F24 | 1.8 | |
12p13.33 | CTD-2094C14 | RP11-574G8 | 0.2 | |
14q32.33 | CTD-2344P12 | RP11-603L1 | 0.4 | AKT1 |
16p13.3 | RP11-344L6 | RP11-680M24 | 3.2 | |
17p13.1 | RP11-205D17 | RP11-63C7 | 0.6 | |
19p13.3 | RP11-519F9 | RP11-81M8 | 1.6 | |
19q13.42 | CTD-2503B7 | RP11-528E9 | 0.3 | |
20q13.33 | CTD-2022N11 | RP11-350G15 | 2.4 | |
Losses (≥ 40%) | ||||
3p26.3-p24.2 | RP11-359E9 | RP11-512O18 | 3.5 | RARB, TOP2B |
3p14.2-p14.1 | RP11-350E21 | RP11-175F9 | 6.9 | FHIT |
3p14.1-p13 | RP11-607B7 | RP11-744B4 | 5.8 | |
5q12.3-q13.1 | RP11-158G8 | RP11-633F2 | 0.9 | PIK3R1 |
8p23.2 | RP11-46M15 | RP11-593J22 | 2.2 | |
9p24.3-p24.2 | RP11-272N16 | RP11-778P24 | 3.1 | MTAP, CDKN2A, CDKN2B |
9p23 | RP11-6H18 | RP11-312G1 | 1.9 | |
9p21.3 | RP11-113D19 | RP11-16P12 | 5.2 | |
11q25 | RP11-217L21 | CTD-2270L17 | 2.4 | ATM |