Table 1 Frequency of Ex4+199 G>C (72Pro) allele
| Â | Â | Genotypic frequencies (%) | P values | Allele frequencies (%) | HWE | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Group | Sampl number e | GG (Arg, Arg) | GC (Arg, Pro) | CC (Pro, Pro) | All cases | BRCA2+ | BRCA- | G | C | P value |
Controls | 112 | 57 (50.9) | 46 (41.1) | 9 (8.0) | 0.84 | Â | Â | 160 (71.4) | 64 (28.6) | 1 |
All cases | 157 | 80 (51.0) | 67 (42.7) | 10 (6.3) | Â | Â | Â | 227 (72.3) | 87 (27.7) | 0.55 |
BRCA1+ | 42 | 20 (47.6) | 18 (42.9) | 4 (9.5) | Â | 0.86 | 0.47 | 58 (69.0) | 26 (31.0) | 1 |
BRCA2+ | 57 | 29 (50.9) | 24 (42.1) | 4 (7.0) | Â | Â | 0.78 | 82 (71.9) | 32 (28.1) | 1 |
BRCA- | 58 | 31 (53.4) | 25 (43.1) | 2 (3.4) | Â | Â | Â | 87 (75.0) | 29 (25.0) | 0.47 |
BRCA1/2+ | 99 | 49 (49.5) | 42 (42.5) | 8 (8.0) | Â | Â | 0.57 | 140 (70.7) | 58 (29.3) | 1 |