|  |  | Relative chance for LC compared to ... | |||
---|---|---|---|---|---|---|
 |  |  | Genetic protected never or light smokers | Genetic protected of the same smoking exposure**.§ | ||
SEL: smoking exposure level | gPS*: count of protective alleles | n cases:controls | OR | 95% CI | OR | 95% CI |
Never and light smoker | 0 | 8:28 | 1.00 | Reference | 1.00 | Reference |
 | 1 | 4:39 | 0.43 | 0.09 – 1.93 | 0.43 | 0.09 – 1.93 |
 | 2 | 2:22 | 0.50 | 0.09 – 2.85 | 0.50 | 0.09 – 2.85 |
 | 3 or 4 | 2:6 | 1.91 | 0.29 – 12.4 | 1.91 | 0.29 – 12.4 |
Moderate smokers | 0 | 15:2 | 24.7 | 4.05 – 150 | 1.00 | Reference |
 | 1 | 20:8 | 12.8 | 3.60 – 45.4 | 0.51 | 0.09 – 2.95 |
 | 2 | 9:11 | 4.1 | 1.07 – 15.4 | 0.17 | 0.03 0.99 |
 | 3 or 4 | 1:0 | -- |  | -- |  |
Heavy smokers | 0 | 40:3 | 74.4 | 16.2 – 341 | 1.00 | Reference |
 | 1 | 57:12 | 25.7 | 8.14 – 81.5 | 0.35 | 0.09 – 1.31 |
 | 2 | 26:7 | 18.9 | 5.15 – 69.2 | 0.25 | 0.06 – 1.08 |
 | 3 or 4 | 6:3 | 10.2 | 1.78 – 58.2 | 0.14 | 0.02 – 0.87 |
All smokers | 0 | Â | Â | Â | 1.00 | Reference |
 | 1 |  |  |  | 0.40 | 0.14 – 1.15 |
 | 2.3.4 |  |  |  | 0.20 | 0.07 – 0.60 |