Skip to main content

Table 3 p-values for Baumgartner-Weiss-Schindler test for genetic association and OR for main genetic effects

From: Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years

Marker

    

Sex

Current smoker

  

Total study pop.

Women

Men

 
  

p-value

OR**

95%-CI

p-values

CYP1A1(Val462Ile)

rs1048943

0.857

0.68

0.30–1.51

1.000

0.838

0.833

GSTP1(A-193C)

rs947895

0.213

0.96

0.62–1.48

0.396

0.138

0.166

EPHX1(His113Tyr)

rs1051740

0.175

0.67

0.44–1.03

0.178

0.419

0.015

EPHX1(Arg139His)

rs2234922

0.366

1.41

0.86–2.30

0.243

0.475

0.342

NAT2(Thr114Ile)

rs1801280

0.445

1.01

0.64–1.59

0.450

0.355

0.131

NAT2(Gln197Arg)

rs1799930

0.252

1.02

0.66–1.55

0.241

0.445

0.291

XPD(Asp312Asn)

rs1799793

0.262

0.96

0.61–1.50

0.437

0.155

0.388

XRCC1(Arg280His)

rs25489

0.417

0.76

0.38–1.50

0.354

0.793

0.624

XRCC1(Arg399Gln)

rs25487

0.385

0.82

0.52–1.29

0.409

0.409

0.453

GPX1(Pro200Leu)

rs1050450

0.002*

0.50

0.32–0.79

0.020

0.011

0.034

p53(Arg72Pro)

rs1042522

0.190

1.14

0.72–1.80

0.127

0.385

0.278

  1. p-values < 0.05 are bold.
  2. * p-values below Bonferroni-corrected significance level of α' = 0.05/11 = 0.0045
  3. ** OR: Odds ratios adjusted for smoking exposure level (SEL), age and sex
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us