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Table 3 Association of molecular positivity in peripheral blood of breast cancer patients with traditional predictors of prognosis.

From: Detection of mammaglobin mRNA in peripheral blood is associated with high grade breast cancer: Interim results of a prospective cohort study

Characteristic

5-gene panel (n = 136)

mam(n = 29)

PSE(n = 58)

Histologic Grade

   

   I

31/63 (49.2%)

3/63 (4.8%)

15/63 (23.8%)

   II-III

98/143 (68.5%)

22/143 (15.4%)

42/143 (29.4%)

 

P = 0.0083

P = 0.0315

P = 0.4110

Nodal Metastases (Path)

   

   N0

97/150 (64.7%)

18/150 (12.0%)

46/150 (30.7%)

   N1

37/64 (57.8%)

10/64 (15.6%)

12/64 (18.8%)

 

P = 0.3427

0.4715

P = 0.0726

ER Status

   

   ER-neg

28/46 (60.9%)

10/46 (21.7%)

6/46 (13.0%)

   ER-pos

98/154 (63.6%)

17/154 (11.0%)

49/154 (31.8%)

 

P = 0.7331

P = 0.0624

P = 0.0123

PR Status

   

   PR-neg

40/67 (59.7%)

11/67 (16.4%)

12/67 (17.9%)

   PR-pos

79/120 (65.8%)

16/120 (13.3%)

42/120 (35.0%)

 

P = 0.4033

P = 0.5650

P = 0.0134

Risk Category

   

   Low/Intermediate Risk

20/34 (58.8%)

2/34 (5.9%)

9/34 (26.5%)

   High Risk

116/181 (64.1%)

27/181 (14.9%)

49/181 (27.1%)

 

P = 0.5861

P = 0.2698*

P = 0.9564

  1. P-values obtained by Chi-square analysis or *Fisher's exact test