Table 2 Multivariable proportional-hazards analyses for the risk of recurrence for patients in sample set I and II

Haptoglobin phenotype

   Hp 1-1

1

-

-

1

-

-

   Hp 2-1

4.21

(0.44 – 39.83)

0.2105

0.94

(0.58 – 1.52)

0.8059

   Hp 2-2

17.76

(2.00 – 157.44)

0.0098

1.26

(0.76 – 2.08)

0.3653

Surgery

   Breast conserving

1

-

-

1

-

-

   Mastectomy

1.26

(0.24 – 6.67)

0.7843

0.91

(0.59 – 1.39)

0.6514

Treatment arm

   High dose

1

-

-

1

-

-

   Conventional dose

0.33

(0.11 – 1.00)

0.0509

1.36

(0.96 – 1.92)

0.0809

Age

   ≥ 40 yrs

1

-

-

1

-

-

   < 40 yrs

1.26

(0.32 – 4.93)

0.7413

0.97

(0.65 – 1.46)

0.8890

No. of positive lymph nodes

   4 – 9

1

-

-

1

-

-

   ≥ 10

0.72

(0.23 – 2.29)

0.5785

1.00

(0.69 – 1.45)

0.9964

Tumour size

   < 5 cm

1

-

-

1

-

-

   ≥ 5 cm

1.35

(0.50 – 3.65)

0.5497

1.63

(1.03 – 2.60)

0.0374

Her2/Neu status

   Negative

1

-

-

1

-

-

   Positive

1.47

(0.53 – 4.08)

0.4641

1.47

(0.99 – 2.20)

0.0589

Receptor status

   ER/PR positive

1

-

-

1

-

-

   ER/PR negative

3.39

(0.80 – 14.27)

0.0962

1.11

(0.73 – 1.70)

0.6138

Bloom-Richardson grade

   Grade I

1

-

-

1

-

-

   Grade II

0.92

(0.26 – 3.23)

0.9016

0.87

(0.50 – 1.50)

0.6187

   Grade III

1.28

(0.37 – 4.46)

0.6946

1.34

(0.79 – 2.26)

0.2796