Variables | Categories | n | HRa | 95 % CI | p-valueb |
---|---|---|---|---|---|
Clark's level of invasion | II, III, IV | 101 | 1 | ||
V | 26 | 2.5 | 1.3–4.7 | 0.007 | |
Tumor necrosis | absent | 86 | 1 | ||
present | 41 | 2.7 | 1.5–4.8 | 0.001 | |
αv-integrin expression | lowc | 37 | 1 | ||
high | 90 | 2.3 | 1.0–5.1 | 0.049 | |
p16 expression | highc | 63 | 1 | ||
low | 64 | 2.5 | 1.4–4.5 | 0.003 |