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Table 2 Expression of cell adhesion proteins in benign melanocytic nevi and cutaneous melanoma

From: Tumor necrosis is associated with increased alphavbeta3integrin expression and poor prognosis in nodular cutaneous melanomas

Cell adhesion markers

No. of cases

pa

 

Nevi

NMb + SSMc

 

α v -integrin

   

   weakd

15

42

 

   strong

16

104

0.034

β3-integrin

   

   weakd

21

53

 

   strong

10

97

0.001

CD44

   

   weakd

8

69

 

   strong

22

77

0.038

osteopontin

   

   weakd

26

60

 

   strong

5

88

< 0.0001

  1. aChi-square test
  2. bNodular melanoma
  3. cSuperficial spreading melanoma
  4. dCut-point median (SI)
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BMC Cancer

ISSN: 1471-2407

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