Figure 1
A – Serous carcinoma. Immunostaining for HIF1α with polyclonal antibody made in the University of Thessaly. B – Serous carcinoma. Immunostaining for HIF1α with rabbit polyclonal antibody (Santa Cruz).note variable cytoplasmic staining in addition to the variable nuclear staining. C – Serous carcinoma. Immunostaining for HIF1α with monoclonal antibody 54/HIF-1α (BD Biosciences). Note focal nuclear staining and lack of cytoplasmic staining. D – Serous carcinoma. Immunostaining for HIF1α with monoclonal antibody H!a67 (Neomarkers). Note focal nuclear staining and lack of cytoplasmic staining. E – Serous carcinoma. Immunostaining for HIF1α with monoclonal antibody H1a67 (Abcam). Note focal and weak nuclear staining and lack of cytoplasmic staining in this case. Cytoplasmic staining was seen in other cases. F – Serous tumor of low malignant potential. Note weak staining in several nuclei and focal intense staining of the nuclei at the tip of the papilla (see arrow and insert). Immunostaining with clone H1a67 (Abcam).