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Table 2 Expected haplotype frequencies between Arg72Pro and PIN3 Ins16bp polymorphisms. Association with familial and sporadic breast cancer risk.

From: Importance of TP53 codon 72 and intron 3 duplication 16bppolymorphisms in prediction of susceptibility on breast cancer

Haplotypes

Positive FH Cases

Controls

OR (95% CI)

Negative FH Cases

Controls

OR (95% CI)

Arg-A1

0.607

0.711

Reference

0.695

0.705

Reference

Arg-A2

0.091

0.041

2.10 (1.08–4.06)

0.048

0.045

1.06 (0.53–2.12)

Pro-A1

0.150

0.111

1.49 (0.86–2.58)

0.098

0.119

0.80 (0.49–1.32)

Pro-A2

0.151

0.137

1.27 (0.72–2.24)

0.160

0.131

1.27 (0.83–1.95)

  1. FH – family history; OR – odds ratio; CI – confidence interval
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BMC Cancer

ISSN: 1471-2407

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