Table 3 NOS3 gene promoter haplotypes, number of copies, and prostate cancer risk.
From: The -786T>C promoter polymorphism of the NOS3gene is associated with prostate cancer progression
Haplotypesa (SSCP Conformation) | Units | Zero Copies | One Copy | p-Value | Two copies | p-Value |
|---|---|---|---|---|---|---|
No mutations (T) | Controls/cases | 17/16 | 48/36 | 0.73 | 29/30 | 1.0 |
OR (95% CI) | 1.00 (ref) | 0.80 (0.36 – 1.79) | 1.10 (0.47 – 2.58) | |||
[-786T>C; -714G>T; -690C>T] (C) | Controls/cases | 42/36 | 44/37 | 0.92 | 8/9 | 0.81 |
OR (95% CI) | 1.00 (ref) | 0.98 (0.52–1.83) | 1.31 (0.46 – 3.76) | |||
[-786T>C; -764A>G; -690C>T] (A) | Controls/cases | 72/71 | 22/11 | 0.13 | 0/2 | -- |
OR (95% CI) | 1.00 (ref) | 0.51 (0.23 – 1.12) | -- | |||
[-786T>C; -690A>G; -649G>A]b (N) | Controls/cases | 94/82 | 0/1 | -- | 0/0 | -- |
OR (95% CI) | 1.00 (ref) | -- | -- |