Table 1 Mean particle size, size distribution (polidispersivity index, PDI), Zeta potential and encapsulation efficiency (EE) of empty PLGA NS and PTX-NS before and after freeze-drying.
Freeze-drying | Mean size (nm) | PDI | Zeta potential (mV) | % E.E. | |
|---|---|---|---|---|---|
PLGA NS | before | 292.20 ± 72.50 | 0.385 ± 0.144 | -5. 20 ± 0.10 | - |
after | 386.76 ± 45.50 | 0.340 ± 0.150 | -4. 60 ± 0.20 | ||
PTX-NS | before | 192.00 ± 18.40 | 0.296 ± 0.071 | -6.20 ± 0.20 | 35.59 ± 2.53 |
after | 286.76 ± 45.50 | 0.340 ± 0.089 | -5.10 ± 0.10 |