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Table 4 Fisher's exact test between RXRs cytoplasmic expression and different clinicopathological data of the patients presenting infiltrative carcinomas.

From: Human pregnane X receptor is expressed in breast carcinomas, potential heterodimers formation between hPXR and RXR-alpha

  

RXR-α C

RXR-β C

RXR-γ C

  

Negative

Weak

High

p-value

Negative

Weak

High

p-value

Negative

Weak

High

p-value

Tumor Type

Ductal

30

3

21

0.264

24

12

18

0.838

19

10

25

0.151

 

Lobular

14

3

5

 

10

6

6

 

13

2

7

 

Age

<50

12

3

4

0.185

10

4

5

0.765

5

3

11

0.254

 

>50

33

3

22

 

25

14

19

 

27

9

22

 

Tumor size

1

15

4

12

0.697

12

11

8

0.292

15

7

9

0.392

 

2

22

2

9

 

17

4

12

 

12

5

16

 
 

3

3

0

2

 

1

2

2

 

2

0

3

 
 

4

5

0

3

 

5

1

2

 

3

0

5

 

Nodal status

-

22

3

10

0.678

17

12

6

0.024

18

9

8

0.003

 

+

23

3

16

 

18

6

18

 

14

3

25

 

ER

0

10

0

7

0.274

6

2

9

0.060

2

3

12

0.000

 

1

6

0

0

 

3

0

3

 

1

0

5

 
 

2

6

2

4

 

4

6

2

 

2

4

6

 
 

3

23

4

15

 

22

10

10

 

27

5

10

 

PR

0

13

1

7

0.296

11

5

5

0.480

9

2

10

0.009

 

1

7

0

0

 

3

0

4

 

0

0

7

 
 

2

8

1

4

 

5

5

3

 

4

5

4

 
 

3

17

4

15

 

16

8

12

 

19

5

12

 
  1. Tumor size (TNM): T = 1, 2, 3, 4. ER and PR: 0 = Negative, 1 = Weak immunoreaction, 2/3 = High immunoreaction. C: Cytoplasmic immunoreaction.