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Table 3 Number of pathways with significant differential expression between N0 and N+ HNSCC in the reference and validation datasets

From: Gene-expression of metastasized versus non-metastasized primary head and neck squamous cell carcinomas: A pathway-based analysis

 

Pathways significant in validation dataset

Pathways not significant in validation dataset

Pathways significant in reference dataset

7

16

Pathways not significant in reference dataset

3

215

  1. In all, 241 different tumorigenesis and metastasis related pathways were tested. 23 significant differentially expressed pathways were found in the reference dataset, and 10 in the validation dataset, 7 of which overlapped. 215 pathways showed no significant differential gene expression in both datasets.
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BMC Cancer

ISSN: 1471-2407

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