Table 3 Associations between frequencies of inferred XPC haplotypes and risk of lung cancer
| Â | Â | Â | Â | Histologic types of lung cancer | |||||
|---|---|---|---|---|---|---|---|---|---|
XPC haplotypesa | Controls | Cases | Adenocarcinomas | Squamous cell | Small cell | ||||
| Â | Â | n (%) | OR (95% CI) | n (%) | OR (95% CI) | n (%) | OR (95% CI) | n (%) | OR (95% CI) |
All subjects | 2022 | 2020 | Â | 860 | Â | 670 | Â | 130 | Â |
   GCCCC | 721 (35.6) | 737 (36.5) | 1.00 | 328 (38.1) | 1.00 | 243 (36.3) | 1.00 | 35 (26.9) | 1.00 |
   GCCTA | 615 (30.5) | 625 (30.9) | 0.99 (0.85–1.16) | 278 (32.3) | 0.99 (0.82–1.21) | 208 (31.0) | 1.00 (0.81–1.24) | 42 (32.3) | 1.41 (0.89–2.23) |
   ACCCA | 453 (22.7) | 414 (20.5) | 0.89 (0.76–1.06) | 160 (18.6) | 0.78 (0.62–0.97)* | 153 (22.8) | 1.00 (0.79–1.27) | 37 (28.5) | 1.68 (1.04–2.71)* |
   ACGCA | 100 (4.6) | 90 (4.4) | 0.88 (0.65–1.19) | 36 (4.2) | 0.79 (0.53–1.18) | 24 (3.6) | 0.71 (0.45–1.14) | 7 (5.4) | 1.44 (0.62–3.33) |
   GGGCA | 74 (3.7) | 78 (3.9) | 1.03 (0.74–1.44) | 33 (3.8) | 0.98 (0.64–1.51) | 22 (3.3) | 0.88 (0.54–1.45) | 6 (4.6) | 1.67 (0.68–4.10) |
   GCGCC | 18 (0.9) | 28 (1.4) | 1.52 (0.83–2.78) | 11 (1.3) | 1.34 (0.63–2.88) | 7 (1.0) | 1.15 (0.48–2.80) | 0 (0.0) | --- |
   Others b | 41 (2.0) | 48 (2.4) | 1.15 (0.75–1.76) | 14 (1.6) | 0.75 (0.40–1.40) | 13 (1.9) | 0.94 (0.50–1.78) | 3 (2.3) | 1.51 (0.44–5.11) |