|  | Bcl-2 expression | P | |
---|---|---|---|---|
 |  | (-) | (+) |  |
Histology | ductal | 55 (39.9) | 83 (60.1) | 0.521 |
 | others | 4 (30.8) | 9 (69.2) |  |
Histologic grade | I, II | 14 (21.2) | 52 (78.8) | < 0.001 |
 | III | 42 (54.5) | 35 (45.5) |  |
Endolymphatic tumor emboli | absent | 2 (33.3) | 4 (66.7) | 1.000 |
 | present | 43 (37.1) | 73 (62.9) |  |
ER | (-) | 52 (76.5) | 16 (23.5) | < 0.001 |
 | (+) | 7 (8.4) | 76 (91.6) |  |
PR | (-) | 55 (59.8) | 37 (40.2) | < 0.001 |
 | (+) | 4 (6.8) | 55 (93.2) |  |
p53 | ≤25% | 33 (31.4) | 72 (68.6) | 0.004 |
 | >25% | 26 (56.5) | 20 (43.5) |  |
c-erbB2 | (-)~(2+) | 42 (34.7) | 79 (65.3) | 0.027 |
 | (3+) | 17 (56.7) | 13 (43.3) |  |
Ki-67 | < 5% | 18 (26.9) | 49 (73.1) | 0.006 |
 | ≥5% | 41 (48.8) | 43 (51.2) |  |