Skip to main content

Table 3 Risk of epithelial ovarian cancer and SHBG-ATP1B2 extended haploptypes, among 264 ovarian cancer cases and 625 controls in the Polish Ovarian Cancer Study

From: Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study

        

Haplotype frequency

OR

95%CI

P

Haplotypes*

Cases

Controls

   

A

T

A

C

C

C

C

G

0.26

0.20

1.00

(reference**)

 

G

.

.

.

.

.

.

.

0.32

0.35

0.77

0.58 – 1.01

0.06

.

.

.

.

.

.

G

A

0.01

0.02

0.43

0.14 – 1.33

0.14

.

.

.

T

.

.

G

.

0.12

0.11

0.89

0.60 – 1.33

0.58

.

.

.

T

.

T

G

A

0.09

0.09

0.83

0.56 – 1.23

0.36

.

.

.

T

T

T

G

A

0.04

0.03

1.22

0.70 – 2.12

0.49

.

.

G

T

.

.

G

A

0.05

0.05

0.81

0.50 – 1.30

0.38

.

C

.

T

.

.

G

.

0.07

0.07

0.81

0.53 – 1.25

0.34

G

.

.

.

.

.

G

.

0.01

0.02

0.51

0.17 – 1.58

0.24

Global p = 0.42

  1. * Polymorphic bases in 5' to 3' order: SHBG (rs1799941, rs6257, rs6259, rs727428, rs1641544); ATP1B2 (rs16441537, rs1624085, rs1641512). Two ATP1B2 SNPs (rs1641536 and rs1641535) highly correlated (r2 > 0.98) with rs1641537 are not included in the analyses.
  2. ** The reference