Table 2 Genes differentially expressed between normal lobular versus normal ductal cells by both rank products and pairwise analysis
Probe Set1 | Gene Symbol | Gene Title | Rank products | Pairwise comparison |
|---|---|---|---|---|
| Â | Â | Â | Fold-change | Incr/Decr |
Regulation of transcription | ||||
229431_at | RFXAP↓ | Regulatory factor X-associated protein | -3.1 | 1/6 |
229732_at | HSZFP36↓ | ZFP-36 for a zinc finger protein | -3.0 | 0/6 |
207117_at | H-plk↑ | Krueppel-related zinc finger protein | 2.4 | 6/1 |
Protein biosynthesis and modification | ||||
214130_s_at | PDE4DIP↓ | Phosphodiesterase 4D interacting protein (myomegalin) | -3.2 | 1/6 |
232752_at | --- (LOXL1) ↓ | CDNA FLJ10302 fis, clone NT2RM2000042 (lysyl oxidase-like 1) | -1.4 | 1/6 |
Proteolysis and metabolism | ||||
49452_at | ACACB↓ | Acetyl-Coenzyme A carboxylase beta | -18 | 0/8 |
220419_s_at | USP25↓ | Ubiquitin specific peptidase 25 | -2.9 | 1/6 |
220177_s_at | TMPRSS3↓ | Transmembrane protease, serine 3 | -2.8 | 1/6 |
Ion transport | ||||
201735_s_at | CLCN3↓ | Chloride channel 3 | -2.8 | 2/6 |
205044_at | GABRP↓ | Gamma-aminobutyric acid (GABA) A receptor, pi | -1.8 | 1/6 |
Actin binding | ||||
212650_at | EHBP1↑ | EH domain binding protein 1 | 2.6 | 6/0 |
GTPase activity | ||||
202975_s_at | RHOBTB3↑ | Rho-related BTB domain containing 3 | 2.5 | 7/1 |
203264_s_at | ARHGEF9↑ | Cdc42 guanine nucleotide exchange factor (GEF) 9 | 2.6 | 6/0 |
Regulation of cell development, activation, growth and motility | ||||
209890_at | TSPAN5↑ | Tetraspanin 5 | 2.6 | 7/0 |
Small leucine-rich proteoglycan (slrp) family | ||||
211896_s_at | DCN↑ | Decorin | 2.0 | 7/1 |
Protein kinase cascade | ||||
211081_s_at | MAP4K5↓ | Mitogen-activated protein kinase kinase kinase kinase 5 | -2.3 | 1/7 |
Other | ||||
206157_at | PTX3↓ | Pentraxin-related gene, rapidly induced by IL-1 beta | -2.8 | 2/7 |
218431_at | C14orf133↓ | Chromosome 14 open reading frame 133 | -2.7 | 0/7 |
218514_at | FLJ10587↓ | Hypothetical protein FLJ10587 | -2.6 | 1/7 |
226760_at | LOC203411↑ | Hypothetical protein LOC203411 | 3.0 | 6/2 |