Figure 5
From: Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line
Dose study of the effect of TGZ on the phosphorylation and expression of FAK and PTEN. ES-2 cells were treated with different doses of TGZ for 24 h (A). The cell homogenates were subjected to Western blot analysis with various antibodies as indicated. Immunoblot results are from a representative experiment performed in triplicate with β-actin as loading control. (B) After densitometric scans of triplicate blots, values for pY397FAK were normalized to total FAK. (C and D) Values for p-PTEN and PTEN were normalized to β-actin. *P < 0.05 vs. DMSO-treated cells.