Concomitant treatment of brain metastasis with Whole Brain Radiotherapy [WBRT] and Temozolomide [TMZ] is active and improves Quality of Life

Table 5 Multivariate analysis for OS and PFS.

Overall Survival (OS)	P value
Tumour control (SD, CR, PR)	0.007
Brain progression (PD)
KPS <70	0.024
KPS ≥ 70
Age ≤ 65 years	0.792
Age > 65 years
RPA 1	0.004
RPA 2
RPA 3
Progression Free Survival (PFS)	P value
Tumor control (SD, CR, PR)	0.001
Brain progression (PD)
KPS <70	0.05
KPS ≥ 70
No extracranial disease	0.810
Extracranial disease
Age > 65 years	0.310
Age ≤ 65 years
RPA 1	0.001
RPA 2
RPA 3

ISSN: 1471-2407