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Table 1 Invasive tumors: patient and tumor characteristics by histological type

From: Prognostic value of histopathology and trends in cervical cancer: a SEER population study

Characteristic

Non-missing data

Microinvasive SCC

Carcinoma not otherwise specified

Squamous Cell (SCC)

Adenoca. excl. mucinous

Adeno-squamous

Mucinous adeno-carcinoma

Small cell carcinoma

  

n = 2910

n = 1688

n = 20755

n = 4015

n = 1120

n = 305

n = 196

Age (1)

30989

38 (31~48)

42 (32~58)

50 (39~64)

47 (37~62)

44 (36~57)

50 (41~66)

48 (35~63)

Marital status (married)(2)

27999

1451 (55%)

736 (52%)

9193 (49%)

2102 (58%)

548 (53%)

160 (57%)

95 (51%)

Race

30764

       

   White non-hisp (2)

 

2041 (71%)

1191 (72%)

13797 (67%)

3066 (77%)

785 (70%)

229 (75%)

127 (65%)

   White hispanic (2)

 

199 (7%)

96 (6%)

1671 (8%)

236 (6%)

75 (7%)

19 (6%)

14 (7%)

   Black (2)

 

362 (13%)

278 (17%)

3430 (17%)

318 (8%)

157 (14%)

23 (8%)

21 (11%)

   Other (2)

 

279 (10%)

95 (6%)

1735 (8%)

357 (9%)

97 (9%)

34 (11%)

32 (16%)

Tumor size (mm) (1)(3)

6352

1 (1~2)

2 (1~53)

40 (17~60)

25 (10~45)

30 (20~50)

29 (20~47)

45 (29~69)

High histological grade (2)

16378

95 (28%)

248 (86%)

5722 (49%)

821 (28%)

485 (70%)

61 (26%)

142 (100%)

Number of nodes removed (1)(4)

14178

0 (0-0)

0 (0-0)

0 (0–9)

0 (0–17)

1 (0–18)

5 (0–21)

0 (0–11)

Node-positive status (2)

5243

1 (0%)

9 (18%)

679 (21%)

143 (12%)

92 (24%)

33 (29%)

21 (48%)

Log odds nodal involvement (1)(5)

4497

-3.4 (-3.9~-2.9)

-3.1 (-3.7~-1.9)

-3.4 (-3.9~-2.5)

-3.6 (-3.9~-2.9)

-3.3 (-3.8~-2.3)

-3.4 (-3.9~-1.9)

-2.7 (-3.7~-1.2)

AJCC Stage (6)

        

   I (2)

8831

1583 (99%)

373 (70%)

4674 (51%)

1657 (71%)

407 (60%)

100 (54%)

37 (32%)

   II (2)

2104

11 (1%)

51 (10%)

1708 (19%)

226 (10%)

74 (11%)

18 (10%)

16 (14%)

   III (2)

2223

7 (0%)

50 (9%)

1771 (20%)

216 (9%)

115 (17%)

35 (19%)

29 (25%)

   IV (2)

1358

4 (0%)

61 (11%)

925 (10%)

226 (10%)

77 (11%)

31 (17%)

34 (29%)

Hysterectomy (2)

17994

1553 (72%)

364 (46%)

5302 (48%)

1966 (68%)

540 (67%)

146 (69%)

63 (47%)

Radiotherapy (2)

30747

128 (4%)

435 (26%)

13084 (64%)

1819 (46%)

643 (58%)

183 (60%)

120 (62%)

  1. (1) Values are: median (lower ~ upper quartiles).
  2. (2) Values are: number of patients (%). Rounded percentages are computed excluding cases with missing data.
  3. (3) Tumor size: 1 = microscopic focus or foci; 2 = non-microscopic but <= 2 mm.
  4. (4) 9678 cases 0 node examined, 4500 cases with >= 1 node examined.
  5. (5) Log ((number of positive nodes +0.5)/(number of negative nodes + 0.5)). More negative values indicate lower risk of nodal involvement [14].
  6. (6) SEER modified stage grouping: Nx cases (unknown nodal status) are grouped according to the T-stage.
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