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Table 1 Correlation of NIS expression and localization with Akt activation and localization

From: PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer

Tumor classification

nuclear pAkt

any pAkt

any pAkt +loss of PTEN

 

n

%

n

%

n

%

NIS-negative tumors

2/7

28

2/7

28*

0/7

0

NIS-positive tumors

16/26

62

19/26

73*

4/25

16

   NIS intracellular (only)

12/19

63

14/19

74

4/18

22

   NIS plasma membrane (any)

4/7

57

5/7

71

0/7

0

  1. * p < .05